neu gene การใช้

• The test looks for extra copies of the HER-2 / neu gene in the nucleus of cancer cells.
• A surprising 30 percent of breast tumors turned out to have too many copies of the HER2 / neu gene.
• The HER-2 / neu gene prompts the production of a protein that is believed to help cancer cells reproduce.
• The test looks for extra copies of a gene known as the HER-2 / neu gene in the nucleus of cancer cells.
• But as the tumors became androgen-independent, the researchers noticed that the activity of the HER-2 / neu gene was spontaneously increased.
• They also showed that by deliberately giving mice extra quantities of the HER-2 / neu gene, the prostate cancers became androgen-independent.
• _More study is needed before women select a specific chemotherapy based on newly discovered genetic risk factors, such as the HER2-neu gene.
• Because her tumor was among the 30 percent that carry the HER-2 / neu genes, Sooy was able to enroll in a Herceptin study at Boston University Medical Center.
• The chances of the cancer recurring are higher for patients with five to 10 copies of the HER-2 / neu gene per cell; most people have two copies per cell.
• By checking whether a woman has extra copies of the HER-2 / neu gene, the test can help doctors determine the scope of the disease and whether further treatment is needed, Turner said.
• In clinical trials of the Oncor test, 31 percent of the patients with localized breast cancer but an elevated number of copies of the HER-2 / neu gene died within five years of surgery, while 97 percent of the patients with normal levels of the gene survived at least five years.
• If the HER-2 / neu gene is indeed involved in making prostate cancer cells androgen-independent,'` we may see a new treatment modality sooner than we thought, " noted Dr . Tapio Visakorpi at the Laboratory of Cancer Genetics at the University of Tampere in Finland in commentary published with the new study.